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Can Cannabis Provide Relief from Ulcerative Colitis Symptoms?

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Ulcerative Colitis is one of the most common chronic inflammatory bowel diseases that target the inner lining of the large intestine. It is estimated that people belonging to the age group of 15 to 30 are the ones most prone to developing Ulcerative Colitis. Now, it is time to come to the big question, can cannabis provide effective relief from symptoms of Ulcerative Colitis? Let’s take a look at the topic from a broader perspective to find an exact answer.

The Impact of Cannabis on Ulcerative Colitis

According to verified sources, cannabis has around 150 cannabinoids present including CBD and delta-9 THC which are the two most studied cannabinoids. The most prominent impact of the cannabinoids is on the CB1 and CB2 receptors of the ECS. These receptors are known to create the brain-gut connection.

Studies have also revealed that both CB1 and CB2 greatly influence the symptoms of Ulcerative Colitis. So, when cannabis is used, it aids in relieving UC symptoms such as nausea/vomiting, chronic pain, intestinal emptying, and increased appetite.

Potential Risks of Using Cannabis for UC

Even though the use of cannabis has a pretty solid ground when it comes to treating certain Ulcerative Colitis symptoms, consulting the gastrointestinal physician who is working on your case before consuming cannabis is the right thing to do. It is important to note that the anti-inflammatory properties of cannabis have been tested on animal subjects but have yet to produce credible results with a prominent effect on CRP (C-Reactive Protein) results.

Apart from this, the following are some potential downsides associated with the use of cannabis,

  • Using cannabis for a long time often increases the risk of getting surgery.
  • Consuming cannabis is not ideal for pregnant ladies.
  • Potential short-term memory loss.
  • Impaired coordination and control.
  • Potential increase in anxiety.

Types of Ulcerative Colitis

Now that we have established a link between the use of cannabis and its beneficial impact on Ulcerative Colitis, let’s take a look at some of the most prominent types of UC.

1. Extensive Colitis

Extensive Colitis can be labeled as the most extended type of UC. Instead of a certain part or section of the large intestine getting affected, Extensive Colitis impacts the whole large intestine causing symptoms like bloody diarrhea, loss of appetite, generalized abdominal pain, and considerable weight loss.

2. Left-sided Colitis

Left-sided Colitis is not as severe as Extensive Colitis, but the inflammation usually begins in the rectum near the sigmoid region leading all the way to the bend in the colon, near the spleen. Prominent symptoms include left-sided abdominal pain, bloody diarrhea, weight loss, and loss of appetite.

3. Ulcerative Proctitis

Ulcerative Proctitis affects only six inches of the rectum, which is the last part of the large intestine. The inflammation is quite concentrated and doesn’t have a notable chance of developing cancer in the long run. Prominent symptoms include rectal bleeding, rectal bleeding, and urgent bowel movements.

Current Research on Cannabis and UC

Quite recently, many researchers have started to further study the impact of medical cannabis on treating IBDs like Ulcerative Colitis. So far, the studies are bringing mixed results with most of the patients claiming that the use of cannabis does in fact have brought some positive changes in their symptoms. Still, we need more groundbreaking research in this sector to establish a strong link between cannabis and its impact on the ECS leading to gastrointestinal relief.

Final Note

So, does cannabis indeed provide relief for prominent ulcerative Colitis symptoms? Well, based on what the majority of the patients have to say, yes, it does. But still, don’t forget to consult your gastrointestinal physician before trying out any cannabis product.

Edward Perez

 

Important Medical Information & Disclaimers

Medical Disclaimer

The content on this page is for informational purposes only. It does not substitute professional medical advice, diagnosis, or treatment. Medical marijuana recommendations are made only by licensed U.S. healthcare providers via secure telemedicine, in accordance with state laws.

Always consult a qualified physician before making any decisions about your health or starting new therapies.

Source: FDA – Cannabis Research & Drug Approval Process

Individual Results May Vary

Medical cannabis affects every patient differently. Outcomes depend on the product chosen, dosing, medical condition, and lifestyle factors like diet, stress, and medication adherence. Effectiveness may vary widely; regular follow-ups with your provider are essential.

Source: NIH – Therapeutic Effects of Cannabis and Cannabinoids

Possible Side Effects

The most common side effects of medical marijuana include dry mouth, dizziness, fatigue, headaches, red eyes, impaired concentration, and increased appetite. Some may experience anxiety, rapid heartbeat, memory issues, or mild hallucinations when using high-THC products. Rare but serious effects include depression, psychosis, heart rhythm changes, and cannabinoid hyperemesis syndrome (frequent vomiting).

Source: Mayo Clinic – Marijuana: Safety and Side Effects

Legal & Regulatory Notice

Medical marijuana is regulated by state law. Marijuana remains a Schedule I substance under U.S. federal law and is not prescribed in the traditional sense; it is recommended or certified for use, not prescribed. Initial evaluations may require in-person visits in certain states; renewals are often available via telemedicine, depending on local regulations.

Sources: DEA – Controlled Substances Act & Telehealth.org – Cannabis Prescribing and Telehealth

Product Quality & Safety

Only purchase medical cannabis from dispensaries licensed and regulated in your state. Unregulated products may contain contaminants or inaccurate THC/CBD concentrations, presenting safety risks.

Source: FDA – What To Know About Cannabis Products

Reporting Side Effects

If you experience unexpected or severe side effects from medical cannabis, notify your provider immediately and report them to the FDA’s MedWatch program: MedWatch Online or call 1-800-FDA-1088.

Your report helps improve safety for all patients.

Source: FDA – MedWatch Safety & Adverse Event Reporting

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